Zejula (niraparib)

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Brand Name : Zejula
Composition : niraparib
Manufactured by : AMGEN.
Strength : 5/10/15/20/25 mg
Form : Tablets
Packing : 60 tablets

 

Prescription Required *

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SKU: ZEJULA Category: Tag:

Description

Buy Zejula (niraparib) Tablets at Anticancercure.com

What is Zejula?

Zejula is used as a “maintenance” treatment to keep certain types of cancer from coming back. This includes cancers of the ovary, fallopian tube, or peritoneum (the membrane that lines the inside of your abdomen and covers some of your internal organs).

Zejula is given after you have received chemotherapy (with cisplatin, oxaliplatin, carboplatin, or similar) and your cancer has responded to that medicine.

Important information

You should not use Zejula if you are pregnant. Avoid pregnancy for at least 6 months after you stop using this medicine.

You should not breast-feed while using Zejula and for at least 1 month after your last dose.

Before taking this medicine

You should not use Zejula if you are allergic to niraparib.

To make sure this medicine is safe for you, tell your doctor if you have:

  • heart disease;
  • high blood pressure; or
  • liver or kidney disease.

Do not use Zejula if you are pregnant. It could harm the unborn baby or cause a miscarriage. Use effective birth control to prevent pregnancy while you are using Zejula and for at least 6 months after your last dose.

You may need to have a negative pregnancy test before starting this treatment.

This medicine may affect fertility (the ability to have children) in men. Talk with your doctor about your individual risk.

It is not known whether niraparib passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using Zejula and for at least 1 month after your last dose.

How should I take Zejula?

Take Zejula exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

You should start taking Zejula no longer than 8 weeks after your most recent chemotherapy treatment with a platinum medicine (cisplatin, oxaliplatin, carboplatin).

You may take this medicine with or without food. Take the medicine at the same time each day.

Zejula is usually taken once a day until your body no longer responds to the medication.

Zejula may be taken at bedtime it upsets your stomach.

Do not crush, chew, break, or open a capsule. Swallow the capsule whole.

Niraparib can lower blood cells that help your body fight infections and help your blood to clot. Your blood will need to be tested often. Your cancer treatments may be delayed based on the results of these tests.

Your blood pressure and heart rate will also need to be checked often.

Store at room temperature away from moisture and heat.

Zejula dosing information

Usual Adult Dose for Ovarian Cancer:

300 mg orally once a day
Duration of Therapy: Until disease progression or unacceptable toxicity

Comments:
-Initiate treatment with this drug no later than 8 weeks after a patient’s most recent platinum-containing regimen.
-Bedtime administration may be a potential method for managing nausea.

Use: Maintenance treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.

Usual Adult Dose for Fallopian Tube Cancer:

300 mg orally once a day
Duration of Therapy: Until disease progression or unacceptable toxicity

Comments:
-Initiate treatment with this drug no later than 8 weeks after a patient’s most recent platinum-containing regimen.
-Bedtime administration may be a potential method for managing nausea.

Use: Maintenance treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.

Usual Adult Dose for Peritoneal Cancer:

300 mg orally once a day
Duration of Therapy: Until disease progression or unacceptable toxicity

Comments:
-Initiate treatment with this drug no later than 8 weeks after a patient’s most recent platinum-containing regimen.
-Bedtime administration may be a potential method for managing nausea.

Use: Maintenance treatment of recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer who are in a complete or partial response to platinum-based chemotherapy.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Zejula?

Follow your doctor’s instructions about any restrictions on food, beverages, or activity.

Zejula side effects

Get emergency medical help if you have signs of an allergic reaction to Zejula: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • pounding heartbeats or fluttering in your chest;
  • sores or white patches in or around your mouth, trouble swallowing or talking, dry mouth, bad breath, altered sense of taste;
  • pain or burning when you urinate;
  • increased blood pressure – severe headache, blurred vision, pounding in your neck or ears, anxiety, nosebleed;
  • low blood cell counts – fever, chills, flu-like symptoms, swollen gums, mouth sores, skin sores, rapid heart rate, pale skin, easy bruising, unusual bleeding, feeling light-headed; or
  • signs of a bone marrow disorder – fever, weakness, tiredness, feeling short of breath, weight loss, blood in your urine or stools.

Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.

Common Zejula side effects may include:

  • indigestion, stomach pain, loss of appetite, nausea, vomiting;
  • constipation, diarrhea;
  • irregular heartbeats, feeling short of breath;
  • abnormal liver function tests;
  • dry mouth, mouth sores;
  • altered sense of taste;
  • back pain, muscle or joint pain;
  • feeling tired;
  • headache, dizziness, anxiety;
  • sleep problems (insomnia);
  • sore throat; or
  • rash.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Follow the following prescription medicine precautions :

  Receiving Zejula while pregnant may indirectly harm the baby by causing side effects in the woman. Take proper medical help in case you are pregnant, may be pregnant or planning to become pregnant in the near future. Health care providers may suggest inducing labor early to protect the baby from cancer treatment.
  You should not be taken Zejula, if you are breast-feeding or plan to breast-feed. This is because the drugs could be passed to your baby through breast milk. As Zejula may cause serious side effects in a breast-fed baby, talk to your doctor about whether you should continue breast-feeding.
  Your doctor will do regular blood tests to check for side effects of Zejula. It is also important to check your levels of blood cells and other substances in the blood.
  Before taking this medicine, tell your doctor and pharmacist if you are allergic to Zejula, any other medications, or any of the ingredients in this cancer medicine. This medication is not recommended for use in patients with a known allergy to Zejula.
  If you take Zejula, you must stop drinking alcohol. This is one of the ways to prevent this disease from getting worse. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.
  If you use other prescription drugs or over the counter products at the same time, the effects of this cancer medicine may change. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that your pharmacist can help you prevent or manage drug interactions.
  More than 80% of patients occasionally miss a dose of their medication. Missing a dose of Zejula can upset your treatment plan. If you miss a dose, contact your health care provider or pharmacist immediately to establish a new dosing schedule. Be careful not to take doses too close together because you might get side effects. Don’t double your next dose to “make up” for the one you missed.
  After the expiry date, medicines may not be safe or lose some or all of their effectiveness. You should not take Zejula after their expiry date. If you’ve had a medicine for a while, check the expiry date before using it. If it has expired or is damaged, return it to your pharmacist for disposal.
  During your treatment with Zejula, it is very important for your doctor to know about your medical history if you have Kidney problems, hepatitis B, liver problems, HIV (human immunodeficiency virus), triglycerides, diabetes or other health problems.

 

What are the storage instructions for Zejula?

Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.

  • Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.
  • Do not use Zejula if the liquid in the vial looks discolored or cloudy, or if the liquid has lumps, flakes, or particles.
  • Keep your medicines separate from those of your spouse or other family members. This will make it less likely that you take the wrong ones by mistake.
  • Do not freeze Zejula injection.

Prescription Required:

We Ship in  USA, UK, China, Canada, Russia, Australia, UAE, Singapore, Philippines, Bulgaria, Hungary, Italy, Kenya, Nigeria, Saudi Arabia, Taiwan, Zimbabwe, Malaysia, Spain, Hong Kong and many other countries.

In order to legally purchase this medicine from Anticancercure.com, you’ll require a prescription from your Registered Medical Practitioner.

Note:

The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Zejula (niraparib)

Additional information

Dose

40mg, 80mg, 125mg

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