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Efavir : Efavirenz 600 Mg Capsules

$99.00

Brand Name : Efavir
Composition : Efavirenz
Manufactured by : Cipla Ltd.
Strength : 600 mg
Form : Capsules
Packing : Pack of 30 Capsules
Prescription Required*
SKU: EFACIP60 Category: Tags: , ,

Description

Buy Efavir : Efavirenz 600 Mg Tablets Online From Anticancercure.com

What is Efavir used for?

Efavir tablets 600mg (also known as Sustiva) are used with other HIV medications as part of combination therapy for the treatment of Human Immunodeficiency Virus (HIV) infection in adults and children three years of age or older. Efavir 600 must not be used alone and is usually combined with two other drugs that have a different mechanism of action; this treatment regime is known as highly active antiretroviral therapy (HAART) and is designed to minimise the ability of the virus to multiply and help prevent development of viral resistance to treatment. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful). Also if too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Efavir tablets 600mg prevent or slow down the ability of HIV to replicate and spread, which keeps the amount virus down to a low level (reduces viral load) and this results in an increase in CD4+ cell numbers, so that the immune system can recover, reducing the risk of disease progression. 

How does Efavir work?

Efavir tablets 600mg (also known as Sustiva) contain efavirenz, a non-nucleoside analogue reverse transcriptase inhibitor (NNRTI), which is only effective against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. Retroviruses convert RNA to DNA, which is then integrated into the DNA of infected immune cells so that the virus can replicate. Efavirenz in Efavir 600 acts by binding to a specific site on the RT enzyme and blocks its action in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA. This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus). Efavir tablets 600mg slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others. 

What does Efavir contain?

Efavir tablets 600mg contains the active ingredient efavirenz, a non-nucleoside analogue reverse transcriptase inhibitors (NNRTI) that is used as part of a combination treatment for Human Immunodeficiency Virus (HIV) infection. 

Treating HIV infection with Efavir

Efavir tablets 600mg (also known as Sustiva) contain efavirenz, an antiretroviral drug that is effective only against RNA viruses (retroviruses) like Human Immunodeficiency Virus (HIV). It works by inhibiting the action of the viral-specific enzyme reverse transcriptase (RT), which is needed for the virus to be able to replicate. HIV impairs the immune system by attacking specific immune cells called CD4+ cells that are involved in fighting infection, and this can lead to opportunistic life-threatening infection (infections that would not normally be harmful), including pneumonia, herpes virus infections, and Mycobacterium avium complex (MAC) infection. If too many CD4+ cells are destroyed this can result in acquired immune deficiency syndrome (AIDS). Efavirenz in Efavir 600 is a non-nucleoside analogue reverse transcriptase inhibitors (NNRTI) and blocks the action of RT in a manner that is noncompetitive with nucleosides (precursors to the building blocks of DNA and RNA), thereby preventing the conversion of viral RNA to DNA. This action prevents the integration of virus into the DNA of the infected CD4+ immune cell, which inhibits the replication of HIV so that no more virus can be produced; and this reduces the viral load (amount of virus). Efavir tablets 600mg slow down the replication of HIV within your body but does not kill the virus already incorporated in the CD4+ cells or prevent the spread of the infection to others. 

What are the side effects of Efavir?

The most commonly reported side effects when taking Efavir tablets 600mg include: skin rash, nausea, dizziness, headache, fatigue. Other less common side effects include, insomnia, drowsiness, inability to concentrate, abnormal dreaming. 

When should Efavir not be used?

You should not use Efavir tablets 600mg if you:

  • are allergic to efavirenz or any ingredients in Efavir
  • are pregnant or are breastfeeding
  • have liver disease
  • are using Efavir 600 as a single treatment as it is intended for use only as part of combination therapy
  • are taking medicines that interact with Efavir, including: other antiretrovirals, such as, amprenavir, indinavir, atazanavir, ritonavir, saquinavir, the antibiotics rifampicin, rifabutin and clarithromycin, the antifungals voriconazole and itraconazole, cholesterol lowering statins like simvastatin and atorvastatin, the antiepileptic carbamazepine, oestrogen containing oral contraceptives, methadone for opioid dependence, the dietary supplement St. John’s Wort, the antidepressant sertraline, calcium channel blockers like diltiazem for angina and hypertension, the antihistamine terfenadine, cisapride for reflux, triazolam for anxiety, the sedative midazolam, ergot derivatives for migraine, the antipsychotic pimozide, bepridil for angina

What medications interact with Efavir?

Several medications interact with Efavir tablets 600mg and should either not be taken while you are taking Efavir or only after discussion and instruction from your doctor: 

  • Drugs that cause a serious reaction with Efavir:, the antihistamine terfenadine, cisapride for reflux, triazolam for anxiety, the sedative midazolam, ergot derivatives for migraine, bepridil for angina
  • Drugs that affect Efavir: other antiretrovirals, such as, ritonavir, amprenavir, atazanavir, indinavir, saquinavir the antibiotic rifampicin, the antiepileptic carbamazepine, the dietary supplement St. John’s Wort,
  • Drugs that are affected by Efavir: the antibiotics rifabutin and clarithromycin, the antifungals voriconazole and itraconazole, cholesterol lowering statins like simvastatin and atorvastatin, the antiepileptic carbamazepine, oestrogen containing oral contraceptives, methadone for opioid dependence, the antidepressant sertraline, calcium channel blockers like diltiazem for angina and hypertension

How should Efavir be taken?

You should take your Efavir tablets 600mg swallowed whole with a glass of water without food, once a day preferably on an empty stomach at bedtime to reduce problems with side effects.  The dose you take depends on your body weight and your doctor’s recommendation.   You should continue to take your Efavir 600 regularly for as long as your doctor recommends, and you condition should be monitored. Do not suddenly stop taking your Efavir tablets as this may increase risk of HIV resistance. 

How long should you take Efavir?

You should continue to take your Efavir 600mg regularly for as long as your doctor recommends, and you condition should be monitored. Do not suddenly stop taking your Efavir tablets as this may increase risk of HIV resistance.

Missed dose of Efavir

If you miss a dose of Efavir tablets 600mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose. 

 

 You need to remember certain points such as –

  

avoid-pregnancy

Efavir medicine may be harmful in pregnancy and there is a potential risk of miscarriage or carrying a child with birth defects if you or your partner becomes pregnant during this time. Also tell your pharmacist if you plan to become pregnant at any time in the future, because Efavir 600Mg may remain in your body for years after you stop taking it.
  It is recommended that women infected with HIV should not breastfeed their infants, regardless of their treatment, in order to avoid transmitting the virus to the baby in the breast milk. To get more information, you should discuss this with your doctor.
  You will need to have regular blood tests and check-ups during your treatment with Efavir. Blood tests help doctors check for certain diseases and conditions. They also help check the function of your organs and show how well treatment is working.
  Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. This HIV medicine is not recommended for use in patients with a known allergy to Daruvir.
  In general, drinking alcoholic beverages should be kept to a minimum or avoided completely. If you are dependent on alcohol and want to stop drinking, your doctor can recommend a therapy that’s tailored for your needs.
  Before using  Efavir, inform your doctor or pharmacist if you are taking or have recently taken any prescription or non-prescription drugs (e.g. vitamins, herbal supplements, etc.), so that your pharmacist can help you prevent or manage drug interactions.
  If you miss a dose of Efavir , take the missed dose as soon as you remember it. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
  Taking a single dose of expired medicine is unlikely to produce an adverse event. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you’ve had a medicine for a while, check the expiry date before using it. If it has expired or is damaged, return it to your pharmacist for disposal.
  Before using Efavir, tell your doctor or pharmacist your medical history, especially if you have liver problems (including hepatitis B or C infection), diabetes, hemophilia (a bleeding disorder), heart or pancreas problems, or low blood potassium levels etc.

 

What are the storage instructions for Efavir?

Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.

  • Store Efavir at 20°C to 25°C (68°F to 77°F); excursions permitted to 15°C to 30°C (59°F to 86°F).
  • Consider storing your medications separately from your other family members. This will make it less likely that you take the wrong ones by mistake.
  • Make sure to always keep your medicine in an area of your home that is out of the reach of children and pets.
  • Store in the original container. Do not use it if the original seal over the container opening is broken or missing.
  • Store Efavir in a dry place (Not in bathroom). Improper storage can affect the effectiveness and shelf life of your medicine.
It is important for you to keep a written list of all of the prescription and nonprescription (over-the-counter) medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
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Prescription Required:

In order to legally purchase this medicine from Anticancercure.com you’ll require a prescription from your Registered Medical Practitioner.

Note:

The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

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