What Is Sandimmun Neoral : Cyclosporine ?
The drug is also marketed under the brand names Neoral, Sandimmune, and Gengraf to reduce the risk of organ transplant rejection.
Restasis is also used to treat a variety of rare eye conditions, including corneal melt, a serious condition often associated with autoimmune disorders such as psoriasis, rheumatoid arthritis or lupus.
Cyclosporine belongs to a group of drugs known as immunosuppressants, which limit the body’s ability to reject what it perceives to be foreign tissue or organs.
The Food and Drug Administration (FDA) first approved cyclosporine in liquid form under the brand name Sandimmune in 1983. Novartis manufactures Sandimmune.
Cyclosporine Use in Organ Transplants
Neoral, Sandimmune, and Gengraf come in capsules or liquid formulations of cyclosporine to be taken by mouth.
Doctors often prescribe it to help reduce the risk of organ rejection in patients who have received an organ transplant.
Restasis has no black-box warnings.
But all forms of cyclosporine taken by mouth have six black-box warnings:
- You shouldn’t switch between dosage forms or brands of oral cyclosporine, because each formulation delivers a different amount of cyclosporine.
- People taking Gengraf are at increased risk of abnormal growth of new cells, which may potentially become cancerous.
- An increased risk of skin cancer may occur in people who have psoriasis — especially if you’re taking or have taken methotrexate or other drugs that weaken the immune system.
- Even at standard doses, cyclosporine may cause high blood pressure or kidney problems.
- Cyclosporine prescribed either for rheumatoid arthritis or to prevent organ transplant rejection requires monitoring.
- Oral forms of cyclosporine should only be administered by trained healthcare professionals in an appropriate medical facility.
You shouldn’t use Restasis if you’re allergic to cyclosporine or any other ingredients found in the drug.
Here are a few important reminders about Restasis:
- Try not to touch the tip of the applicator with your hands, to any part of your eye, or to any other object.
- Don’t wear your contact lenses while applying the drops to your eyes.
- It’s okay to use artificial tears while using Restasis, but remember to apply Restasis first and wait 15 minutes before using the next eye drops.
Pregnancy and Cyclosporine
There is some evidence that cyclosporine may cause harm to a developing fetus.
Your doctor will determine whether the benefit of using the drug is worth the risk to your unborn baby.
Cyclosporine is found in breast milk. Experts don’t recommend using this medication while breastfeeding.
It’s always a good idea to talk to your doctor about all medications you’re taking if you’re pregnant, might become pregnant, or are breastfeeding.
You need to remember certain points such as –
|If you are a woman who is pregnant or wants to have a baby and you are taking cyclosporine, let your doctor know right away. This medicine may cause harm to the unborn baby. Use a birth control method while you are taking this immunosuppressive medicine. Ask your doctor to help you choose a method of birth control that will work for you.|
|For the safety of the baby, breastfeeding isn’t recommended during treatment. Many immunosuppressive drugs like cyclosporine, may appear in high levels in breast milk and could potentially harm your nursing baby. To get more information, you should discuss this with your doctor. Your health care provider might recommend that you stop breast-feeding temporarily or permanently — depending on how long you need to take the medication.|
|You will need to have regular blood tests and check-ups during your treatment with cyclosporine. Blood tests are done to help watch your body’s response to treatment. They can show small changes before problems get serious. Keeping track of your results lets your doctor take action as soon as your blood counts change to help prevent many kidney-related problems and renal treatment side effects.|
|Tell your doctor if you have ever had any unusual or allergic reaction to cyclosporine drug or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes or preservatives. For non-prescription products, read the label or package ingredients carefully.|
|Whether it’s safe to drink alcoholic beverages during treatment with cyclosporine depends on a number of factors, including which drugs the patient is receiving. Alcohol can interfere with the way some haemo-oncology drugs work, so patients should speak with their doctors about any potential side effects of drinking during treatment.|
|Always consult your doctor and pharmacist about taking any other prescription or non-prescription medication, including herbs, supplements and street drugs. This medicine may affect the way other medicines or products work, and other medicines or products may affect how tacrolimus works. Taking cyclosporine together with certain medicines or products may cause serious side effects.|
|If you miss a dose of cyclosporine, take the missed dose as soon as you remember it. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.|
|Taking a single dose of expired medicine is unlikely to produce an adverse event. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you’ve had a medicine for a while, check the expiry date before using it. If it has expired or is damaged, return it to your pharmacist for disposal.|
|Before using cyclosporine, tell your doctor or pharmacist your medical history, especially if you have liver problems (including hepatitis B or C infection), diabetes, high blood pressure, cancer, heart or pancreas problems, or low blood potassium levels etc.|
What are the storage instructions for cyclosporine ?
Patients must properly store the drug to retain its quality and efficacy. Following storage instructions will be helpful in storing the drug in the best of manner.
- Store cyclosporine 100mg Tablets at 2°C to 8°C (36°F to 46°F).
- Consider storing your medications separately from your other family members. This will make it less likely that you take the wrong ones by mistake.
- Store the medicine in a safe place out of the reach of children and pets.
- Keep this medicine away from heat, light and humidity. Improper storage can affect the effectiveness and shelf life of your medicine.
- Do not Store cyclosporine in a refrigerator. Do not freeze.
In order to legally purchase this medicine from anticancercure.com, you’ll require a prescription from your Registered Medical Practitioner.
The information provided here is for general educational purposes only and does not constitute medical or pharmaceutical advice which should be sought from qualified medical and pharmaceutical advisers.
Remember, keep this and all other medicines out of the reach of children and away from pets, never share your medicines with others, and use this medication only for the indication prescribed.
The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.